产品货号:
Z23747
中文名称:
PNK/PNKP抗体
英文名称:
Anti-PNK/PNKP Antibody
产品规格:
100μg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PNK/PNKP Antibody |
指标别名 | DEM1;EIEE10;MCSZ;PNK1;Pnkp;PNKP DNA kinase |
克隆性 | Polyclonal |
检验物种 | human,chimpanzee |
应用范围 | ELISA,WB |
基因名称 | PNKP |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human PNK protein. |
成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
纯化方式 | This affinity purified antibody is directed against human PNK protein.The product was affinity purified from monospecific antiserum by immunoaffinity chromatography.A BLAST analysis was used to suggest reactivity with this protein from human and chimpanzee based on 100% homology for the immunogen sequence.Expect cross-reactivity with PNK from dog,mouse and rat sources,as only two amino acid residues change within the immunogen sequence (83% positive by BLAST).Cross-reactivity with PNK homologues from other sources has not been determined. |
浓度 | 1.46mg/mL by UV absorbance at 280nm |
产品形态 | 溶液 |
保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
背景资料 | Mammalian PNK (also known as PNKP,Polynucleotide kinase 3'-phosphatase,DNA 5'-kinase/3'-phosphatase and Polynucleotide kinase) catalyzes the 5* phosphorylation of nucleic acids and can have associated 3* phosphatase activity,predictive of an important function in DNA repair following ionizing radiation or oxidative damage.PNK is a nuclear protein that is expressed in many tissues with highest expression in spleen and testis,and lowest expression in small intestine. |
Uniprot ID | Q96T60 |
推荐稀释比 | ELISA:1:3,000 - 1:12,000 WB:1:300 - 1:1,500 |
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